Monday, December 19, 2016

                                 19 DECEMBER 2016

                                     DYSKINESIA DOSE SUSCEPTABILITY RANGE
                                            BY SAMUEL D. MOORE

I have found that my dyskinesia has a suscepability range.  The range starts at about 100mgs  of levodopa IR and continues at higher levedopa levels as far as I have experienced.  The Figure below shows the range I have experienced.   The intensity of the dyskinesea, when it occurs, is proportional to the highest level just before the elimination period starts.  At levels less than the suscepable range is a safe range.  
This range starts at a level where the tremors cease.  


The information is patient sensitive and will not be the same for everyone.  Relating the information to blood concentration, one hundred mgs. Is equivalent to approximately 18.2 mg/ml blood concentration.  For my body weight, about 5.5 liters of blood.  
 

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